First report of knockdown mutations in the malaria vector Anopheles gambiae from Cameroon.

نویسندگان

  • Josiane Etang
  • Etienne Fondjo
  • Fabrice Chandre
  • Isabelle Morlais
  • Cecile Brengues
  • Philippe Nwane
  • Mouhamadou Chouaibou
  • Hamadou Ndjemai
  • Frédéric Simard
چکیده

We report the first finding of the knockdown Leu-Phe and Leu-Ser mutations associated with resistance to pyrethroids and DDT insecticides in the malaria mosquito Anopheles gambiae from Cameroon. The Leu-Phe mutation was found in both the M and S molecular forms of An. gambiae. Importantly, two specimens of the S molecular form were found to carry both mutations in a heterozygous state.

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عنوان ژورنال:
  • The American journal of tropical medicine and hygiene

دوره 74 5  شماره 

صفحات  -

تاریخ انتشار 2006